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R44AG066360

Project Grant

Overview

Grant Description
Care4AD: A Comprehensive Care Coordination and Management Platform for Alzheimer Disease and Related Dementias
Awardee
Funding Goals
NOT APPLICABLE
Grant Program (CFDA)
Place of Performance
Massachusetts United States
Geographic Scope
State-Wide
Analysis Notes
Amendment Since initial award the End Date has been extended from 04/30/23 to 05/31/25 and the total obligations have increased 558% from $450,000 to $2,960,344.
Biosensics was awarded Project Grant R44AG066360 worth $2,960,344 from National Institute on Aging in June 2020 with work to be completed primarily in Massachusetts United States. The grant has a duration of 5 years and was awarded through assistance program 93.866 Aging Research. The Project Grant was awarded through grant opportunity Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional).

SBIR Details

Research Type
SBIR Phase II
Title
Care4AD: A Comprehensive Care Coordination and Management Platform for Alzheimer Disease and Related Dementias
Abstract
Care for persons with dementia requires constant and effective management and coordination of delivery of care between caregivers and family members. A robust, technology-driven solution for care management and coordination could significantly reduce the burden of caregiving and improve quality of life for patients with Alzheimer’s disease (AD). A few attempts have been made to use technology to support care coordination, but there is no integrated system to support self-care, assist caregivers with care coordination, and facilitate information sharing within a patientandapos;s caregiving team. In response to this need, BioSensics, in collaboration with Baylor College of Medicine (BCM), proposes to develop a comprehensive care platform called Care4AD™. The Care4AD platform will allow caregivers to schedule caregiving tasks, monitor physical activity and activities of daily living (ADL), and facilitate timely completion of ADLs (e.g., taking medication, scheduled toileting, hydration and meals, and attendance at scheduled appointments) through visual and voice reminders. Care4AD will consist of four technologies that work in tandem to enable effective care coordination. The Care4AD app will be used by caregivers to coordinate care, view physical activity and ADL information, and schedule reminders. The Care4AD tablet serves as a kiosk in the patient’s home to show scheduled activities and reminders, and it also supports audio reminders and voice recognition. Care4AD tags are a series of wireless sensors that will be attached to various objects of interest within the home to facilitate the monitoring of instrumental activities of daily living. Finally, the Care4AD sensor is a wearable sensor (based on existing commercially available technology from BioSensics) that monitors physical activity and ADLs, collects data from the tags, and transfers data to the Care4AD tablet, which serves as a data gateway for all the data collected from the sensor and tags. BioSensics has the requisite experience to successfully complete this project having developed and commercialized a sensor-based remote monitoring platform for older adults called PAMSys™. For this project, we have conducted three preliminary studies using PAMSys to monitor physical activity in individuals with cognitive impairment. In addition, BioSensics has already developed a prototype of the Care4AD tag, which will be further refined in this project. In Phase I, we will develop a prototype of the Care4AD platform and carry out stakeholder interviews to assess the feasibility and acceptability of Care4AD and gather feedback that will be used to improve the platform. In Phase II, we will complete the development of Care4AD, incorporating feedback from Phase I, and carry out a randomized controlled clinical study to evaluate if using the Care4AD platform reduces the burden and stress of caregiving, increases adherence to scheduled ADLs, and improves physical function and quality of life of patients.
Topic Code
NIA
Solicitation Number
PAS19-316

Status
(Ongoing)

Last Modified 8/20/24

Period of Performance
6/15/20
Start Date
5/31/25
End Date
98.0% Complete

Funding Split
$3.0M
Federal Obligation
$0.0
Non-Federal Obligation
$3.0M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to R44AG066360

Transaction History

Modifications to R44AG066360

Additional Detail

Award ID FAIN
R44AG066360
SAI Number
R44AG066360-2211897761
Award ID URI
SAI UNAVAILABLE
Awardee Classifications
Small Business
Awarding Office
75NN00 NIH NATIONAL INSITUTE ON AGING
Funding Office
75NN00 NIH NATIONAL INSITUTE ON AGING
Awardee UEI
C9MRZK4B7K39
Awardee CAGE
4TN46
Performance District
MA-90
Senators
Edward Markey
Elizabeth Warren

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
National Institute on Aging, National Institutes of Health, Health and Human Services (075-0843) Health research and training Grants, subsidies, and contributions (41.0) $1,730,172 100%
Modified: 8/20/24