Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)

Background
The National Institutes of Health (NIH), specifically the National Institute of Mental Health (NIMH) and the National Institute on Drug Abuse (NIDA), is issuing a funding opportunity titled 'Multimodal Artificial Intelligence to Accelerate HIV Clinical Care (R01 Clinical Trial Optional)'. This initiative aims to leverage cutting-edge advances in multimodal artificial intelligence (AI) to enhance HIV diagnosis, prevention, and treatment efforts. It aligns with the mission of NIMH to transform the understanding and treatment of mental illnesses through research.

Grant Details
The funding opportunity seeks innovative projects focused on three primary objectives:

(1) Development, adaptation, and evaluation of accurate, safe, efficient, and unbiased multimodal AI models for diverse HIV applications;

(2) Creation of knowledge graphs to enhance interpretability and explainability for applications in HIV research, clinical care, and public health;

(3) Exploration of synergistic integration of model-based explainability methods, knowledge graphs, and multimodal AI models.

Applicants must propose projects that integrate at least two different modalities of data from at least two sources. The application should detail the model development process including training design, stakeholder integration, challenges faced, and considerations regarding equity and biases.

Eligibility Requirements
Eligible applicants include higher education institutions (public or private), nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), local/state governments, tribal governments, federal agencies, and other organizations. Individuals from diverse backgrounds are encouraged to apply.

Period of Performance
The maximum project period is five years. Specific timelines for project milestones will depend on the proposed scope of work.

Grant Value
The NIMH intends to commit $2 million total costs to fund two awards while NIDA intends to commit $2 million total costs to fund 3-4 awards. Application budgets are limited to $750,000 in direct costs per year.

Place of Performance
The specific geographic locations for performance are expected to align with the goals of addressing the HIV epidemic.