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Lewy Body Dementia Center Without Walls (CWOW) (U54 Clinical Trial Not Allowed)

ID: RFA-NS-19-013 • Type: Posted

Description

This FOA invites applications that will systematically and comprehensively characterize alpha-synuclein and amyloid-beta subspecies present in human Lewy Body Dementia (LBD) post-mortem brain tissue, identify toxic subspecies and potential mechanisms of toxicity, and characterize any interactions between the proteins that may contribute to increased toxicity and/or explain selective vulnerabilities of cells/circuits. Applications are required to include at least 3 hypothesis-driven projects that address these goals, an administrative core, and other cores as appropriate. Applicants will be expected to focus on the use of human tissues. All applications will be expected to include plans for developing a publicly-available library of fully characterized alpha-synuclein and amyloid-beta subspecies found in LBD.

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 10/29/18 the National Institutes of Health posted grant opportunity RFA-NS-19-013 for Lewy Body Dementia Center Without Walls (CWOW) (U54 Clinical Trial Not Allowed) with funding of $3.5 million. The grant will be issued under grant program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.

Timing

Posted Date
Oct. 29, 2018, 12:00 a.m. EDT
Closing Date
Jan. 4, 2019, 12:00 a.m. EST Past Due
Last Updated
Oct. 29, 2018, 1:10 p.m. EDT
Version
1
Archive Date
Feb. 9, 2019

Eligibility

Eligible Applicants
City or township governments
Public and State controlled institutions of higher education
Small businesses
State governments
Private institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Special district governments
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public housing authorities/Indian housing authorities
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Award Sizing

Ceiling
Not Listed
Floor
Not Listed
Estimated Program Funding
$3,500,000
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Contact Email
Email Description
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
Contact Phone
(301) 496-3405

Documents

Posted documents for RFA-NS-19-013

Grant Awards

Grants awarded through RFA-NS-19-013

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