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Combating Antibiotic Resistant Bacteria (CARB) Biopharmaceutical Accelerator

ID: EP-IDS-16-001 • Type: Posted

Description

The current pipeline of candidate antimicrobial products is insufficient to counter the threat of antimicrobial resistance . A novel collaborative model is needed to spur innovation and investment towards new antimicrobial products to repopulate the early development pipeline. In 2014, the United States Government released the National Strategy for Combating Antimicrobial Resistant Bacteria. A component of the National Strategy is to establish a Biopharmaceutical Accelerator for Combating Antibiotic-Resistant Bacteria [Accelerator] to fund Research and Development (R&D) activities to help progress candidate products from the proof-of-concept stage through pre-clinical development. Candidates that graduate from the Accelerator will be better positioned for R&D investment and clinical development. There are various Accelerator models in the marketplace. The Biomedical Advanced Research and Development Authority (BARDA) and the National Institute of Allergy and Infectious Diseases (NIAID) Accelerator will be a non-equity accelerator that provides non-dilutive funding to product developers for R&D activities and enables the product developers to retain full ownership and control of their company. The Accelerator for CARB will be focusing only on antibacterial products. BARDA will provide direct funding and NIAID will provide in-kind services (e.g. preclinical services, technical expertise) to the Accelerator [the cooperative agreement recipient] that will manage a portfolio of investments of early stage antimicrobial product candidates.

Overview

Category of Funding
Science and Technology and other Research and Development
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 2/17/16 the HHS Office of the Assistant Secretary for Preparedness and Response posted grant opportunity EP-IDS-16-001 for Combating Antibiotic Resistant Bacteria (CARB) Biopharmaceutical Accelerator with funding of $250.0 million. The grant will be issued under grant program 93.360 Biomedical Advanced Research and Development Authority (BARDA), Biodefense Medical Countermeasure Development. It is expected that one grant will be made worth between $30.0 million and $30.0 million.

Timing

Posted Date
Feb. 17, 2016, 12:00 a.m. EST
Closing Date
April 15, 2016, 12:00 a.m. EDT Past Due
Closing Date Explanation
Applications must be submitted electronically through www.grants.gov by the application deadline of April 15, 2016 at 11:59PM EDT. ASPR will not accept any applications that are not submitted electronically via www.grants.gov.
Version
9
Archive Date
May 15, 2016

Eligibility

Eligible Applicants
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Small businesses
Public and State controlled institutions of higher education
Private institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Research institutions and Non-domestic (non-U.S.) entities are eligible. Application Screening Criteria Applications that fail to meet the screening criteria described below will not be reviewed and will receive no further consideration. 1. Applications must be submitted electronically via http://www.grants.gov by April 15, 2016 at 11:59PM EDT 2. Applicants are required to send a letter of intent to the program office by March 10, 2016 at 11:59PM EST outlining the project abstract and approximate funding request. Letters of intent should be sent by email to the attention of Dr. Joseph Larsen at joseph.larsen@hhs.gov. Please see “Attachment F: Letter of Intent” for additional instructions and a template. 3. A pre-application workshop will be held on March 3, 2016 from 3:00PM – 5:00PM EST in the Hubert H. Humphrey Building, in the Auditorium, located at 200 Independence Ave SW, Washington, DC 20201 RSVP to this meeting by emailing, Dr. Joseph Larsen at joseph.larsen@hhs.gov, Subject Line: “RSVP for Accelerator Pre-Application Workshop” by February 29, 2016 at 5:00 PM EST. Please include Names, Titles, Organizations, Email, Phone and country of citizenship for each member on your team that will attend. 4. A Technical Assistance Conference Call will be held for only parties that have submitted “Letters of Intent” on March 18, 2016 at 11:00AM EST. This meeting is designed to address any questions associated with an application process. BARDA will address any clarifying questions submitted with the “Letter of intent.” A conference call number will be provided prior to the meeting to only parties that have submitted “letters of Intent”

Award Sizing

Ceiling
$30,000,000
Floor
$30,000,000
Estimated Program Funding
$250,000,000
Estimated Number of Grants
1

Contacts

Contact
Assistant Secretary for Preparedness and Response
Contact Email
Email Description
Grants.gov Customer Support
Additional Information
Combating Antibiotic Resistant Bacteria (CARB) Biopharmaceutical Accelerator

Documents

Posted documents for EP-IDS-16-001

Grant Awards

Grants awarded through EP-IDS-16-001

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