Cmx Reagent Kits from Nanostring Technologies Inc (Ambis 2230794)

This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Nanostring Technologies, 530 Fairview Avenue North, Seattle, WA 98109-5553, United States to procure Nanostring Technologies Inc's CMx reagents for ongoing research.

The National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. Within NIAID, the Laboratory of Malaria and Vector Research (LMVR) is dedicated to studies of malaria and insect vectors of infectious diseases. Research groups in the laboratory maintain an array of on-campus and overseas activities investigating disease-transmitting insects and broad areas of malaria biology and pathogenesis.

Project Background

The CosMx is the a platform to provide spatial multiomics with formalin-fixed paraffin-embedded (FFPE) and fresh frozen (FF) tissue samples at cellular and subcellular resolution. We acquired the machine last year in our laboratory and no other competitor reagents can be used with this machine. CosMx SMI enables rapid quantification and visualization of up to 6,000 RNA and 100 validated protein analytes. It is the flexible, spatial single-cell imaging platform that will drive deeper insights for cell atlas, tissue phenotyping, cell-cell interactions, cellular processes, and biomarker discovery. Only one responsible known source is nanoString that can provide the required reagents to work with the CosMx SMI instrument.

Description of Need:

1. CMx RNA Inst Buffer Kit, Med, Item 100481, Qty 4
2. CMx Hs 6K Discovery RNA Panel, Item 121500041, Qty 2
3. CMx RNA 6Kplx 2sl Img Tray Kit, Item 122000158, Qty 4
4. S&H 9 - 32 Kits / Slides, Item SH0004, Qty 1

Only one award will be made as a result of this solicitation. This will be awarded as a firm-fixed price type of contract.

Delivery: Estimate delivery has a 30 days ARO after receipt and acceptance of award.

Delivery Location: NIH/NIAID/LMVR, 12745 Twinbrook Parkway, Rockville, MD 20852.

The statutory authority for this sole source requirement is 41 U.S.C. 253 (c) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A SOLICITATION FOR COMPETITIVE QUOTATIONS. All responsible sources that could provide the required services may submit a capability statement that will be considered by email (subject line to reference NOI-NIAID-24-2230794) to Rita Davis at rita.davis@nih.gov , by 4:00pm eastern standard time August 16, 2024. All responses received by the closing date of this synopsis will be considered by the Government. Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.